2NQ3
Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Itchy homolog E3 ubiquitin protein ligase | polymer | 173 | 19201.7 | 1 | UniProt (Q96J02) Pfam (PF00168) | Homo sapiens (human) | Itch, Atrophin-1-interacting protein 4, AIP4, NFE2-associated polypeptide 1, NAPP1 |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 1 - 155 (UniProt: Q96J02)
| PDB | External Database | Details |
|---|---|---|
| Met -17 | - | cloning artifact |
| His -16 | - | cloning artifact |
| His -15 | - | cloning artifact |
| His -14 | - | cloning artifact |
| His -13 | - | cloning artifact |
| His -12 | - | cloning artifact |
| His -11 | - | cloning artifact |
| Ser -10 | - | cloning artifact |
| Ser -9 | - | cloning artifact |
| Gly -8 | - | cloning artifact |
| Arg -7 | - | cloning artifact |
| Glu -6 | - | cloning artifact |
| Asn -5 | - | cloning artifact |
| Leu -4 | - | cloning artifact |
| Tyr -3 | - | cloning artifact |
| Phe -2 | - | cloning artifact |
| Gln -1 | - | cloning artifact |
| Gly 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19201.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 19237.2 |






