2NOJ

Crystal structure of Ehp / C3d complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	Complement C3	polymer	297	33143.9	4	UniProt (P01024) Pfam (PF07678)	Homo sapiens (human)
2	B, D, F, H (B, D, F, H)	Efb homologous protein	polymer	80	9596.2	4	UniProt (Q99UV2)	Staphylococcus aureus subsp. aureus Mu50
3	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	71	Chemie (HOH)

Sequence modifications

A, C, E, G: 996 - 1287 (UniProt: P01024)

PDB	External Database	Details
Gly 991	-	expression tag
Ser 992	-	expression tag
Arg 993	-	expression tag
Ser 994	-	expression tag
Thr 995	-	expression tag
Ala 1010	Cys 1010	engineered mutation

B, D, F, H: 30 - 109 (UniProt: Q99UV2)

PDB	External Database	Details
Glu 63	Asn 63	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	170960.2
All*	Total formula weight	170960.2

*Water molecules are not included.