2NO9
The structure of deoxycytidine kinase complexed with troxacitabine and ADP.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | deoxycytidine kinase | polymer | 280 | 32659.6 | 2 | UniProt (P27707) Pfam (PF01712) In PDB | Homo sapiens (human) | dCK |
2 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
3 | A, B | 4-AMINO-1-[(2S,4S)-2-(HYDROXYMETHYL)-1,3-DIOXOLAN-4-YL]PYRIMIDIN-2(1H)-ONE | non-polymer | 213.2 | 2 | Chemie (LTT) | |||
4 | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 260 (UniProt: P27707)
PDB | External Database | Details |
---|---|---|
Met -19 | - | cloning artifact |
Gly -18 | - | cloning artifact |
Ser -17 | - | cloning artifact |
Ser -16 | - | cloning artifact |
His -15 | - | cloning artifact |
His -14 | - | cloning artifact |
His -13 | - | cloning artifact |
His -12 | - | cloning artifact |
His -11 | - | cloning artifact |
His -10 | - | cloning artifact |
Ser -9 | - | cloning artifact |
Ser -8 | - | cloning artifact |
Gly -7 | - | cloning artifact |
Leu -6 | - | cloning artifact |
Val -5 | - | cloning artifact |
Pro -4 | - | cloning artifact |
Arg -3 | - | cloning artifact |
Gly -2 | - | cloning artifact |
Ser -1 | - | cloning artifact |
His 0 | - | cloning artifact |
Ser 9 | Cys 9 | engineered mutation |
Ser 45 | Cys 45 | engineered mutation |
Ser 59 | Cys 59 | engineered mutation |
Ser 146 | Cys 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65319.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1280.8 | |
All* | Total formula weight | 66600.0 |