2NNI
CYP2C8dH complexed with montelukast
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 2C8 | polymer | 476 | 54054.2 | 1 | UniProt (P10632) Pfam (PF00067) | Homo sapiens (human) | CYPIIC8; P450 form 1; P450 MP-12/MP-20; P450 IIC2; S-mephenytoin 4-hydroxylase |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 4 | D (A) | MONTELUKAST | non-polymer | 586.2 | 1 | Chemie (MTK) | |||
| 5 | E (A) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 6 | F (A) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 28 - 490 (UniProt: P10632)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | expression tag |
| Ala 20 | - | expression tag |
| Lys 21 | - | expression tag |
| Lys 22 | - | expression tag |
| Thr 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Ser 25 | - | expression tag |
| Lys 26 | - | expression tag |
| Gly 27 | - | expression tag |
| His 491 | - | expression tag |
| His 492 | - | expression tag |
| His 493 | - | expression tag |
| His 494 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54054.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1555.2 | |
| All* | Total formula weight | 55609.3 |
