2NL8
The origin binding domain of the SV40 large T antigen bound non specifically to a 17 bp palindrome DNA (sites 1 and 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | W | 18-nt PEN element of the SV40 DNA origin | polymer | 18 | 5477.5 | 1 | |||
| 2 | A | large T antigen | polymer | 133 | 15364.6 | 1 | UniProt (P03070) Pfam (PF02217) UniProt (by SIFTS) (Q98ZP7) In PDB | Simian virus 40 | |
| 3 | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 131 - 259 (UniProt: P03070)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | cloning artifact |
| Ser 128 | - | cloning artifact |
| His 129 | - | cloning artifact |
| Met 130 | - | cloning artifact |
| Ser 216 | Cys 216 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20842.2 | |
| All* | Total formula weight | 20842.2 |
