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2N8R

Productive complex between MMP-12 and synthetic triple-helical collagen, revealed through paramagnetic NMR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Macrophage metalloelastasepolymer16418235.41UniProt (P39900)
Pfam (PF00413)
Homo sapiens (human)MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12
2B, C, D
(B, C, D)
Collagen triple helix repeat family proteinpolymer363291.43
3E, F
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
4G, H, I
(A)
CALCIUM IONnon-polymer40.13Chemie (CA)
5J
(A)
waterwater18.01Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight28109.8
Non-Polymers*Number of molecules5
Total formula weight251.1
All*Total formula weight28360.8
*Water molecules are not included.

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PDB entries from 2025-12-24

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