2MZI
NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) in Complex with Anionic Membrane
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Matrilysin | polymer | 250 | 27912.6 | 1 | UniProt (P09237) Pfam (PF01471) Pfam (PF00413) In PDB | Homo sapiens (human) | Matrin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, Uterine metalloproteinase |
| 2 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 126 | Chemie (PX4) | |||
| 5 | A | CHOLEST-5-EN-3-YL HYDROGEN SULFATE | non-polymer | 466.7 | 6 | Chemie (C3S) |
Sequence modifications
A: -2 - 247 (UniProt: P09237)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Glu 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27912.6 | |
| Non-Polymers* | Number of molecules | 136 |
| Total formula weight | 88557.7 | |
| All* | Total formula weight | 116470.3 |
