2MSR
Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase 2A | polymer | 21 | 2272.3 | 1 | UniProt (Q03164) | Homo sapiens (human) | Lysine N-methyltransferase 2A, ALL-1, CXXC-type zinc finger protein 7, Myeloid/lymphoid or mixed-lineage leukemia, Myeloid/lymphoid or mixed-lineage leukemia protein 1, Trithorax-like protein, Zinc finger protein HRX, MLL cleavage product N320, N-terminal cleavage product of 320 kDa, p320, MLL cleavage product C180, C-terminal cleavage product of 180 kDa, p180 |
| 2 | B (B) | PC4 and SFRS1-interacting protein | polymer | 88 | 10260.0 | 1 | UniProt (O75475) Pfam (PF11467) | Homo sapiens (human) | CLL-associated antigen KW-7, Dense fine speckles 70 kDa protein, DFS 70, Lens epithelium-derived growth factor, Transcriptional coactivator p75/p52 |
Sequence modifications
B: 344 - 426 (UniProt: O75475)
| PDB | External Database | Details |
|---|---|---|
| Ser 339 | - | expression tag |
| Asn 340 | - | expression tag |
| Ala 341 | - | expression tag |
| Ala 342 | - | expression tag |
| Ser 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 12532.3 | |
| All* | Total formula weight | 12532.3 |
