2MPG
Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Insulin A chain | polymer | 21 | 2383.7 | 1 | UniProt (P01308) | Homo sapiens (human) | Insulin B chain, Insulin A chain |
| 2 | B (B) | Insulin B chain | polymer | 30 | 3462.0 | 1 | UniProt (P01308) Pfam (PF00049) | Homo sapiens (human) | Insulin B chain, Insulin A chain |
Sequence modifications
B: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Aib 8 | Gly 32 | engineered mutation |
| Lys 28 | Pro 52 | engineered mutation |
| Pro 29 | Lys 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 5845.7 | |
| All* | Total formula weight | 5845.7 |






