2MOE
Solution structure of MBD4 methyl-cytosine binding domain bound to methylated DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyl-CpG-binding domain protein 4 | polymer | 71 | 8088.2 | 1 | UniProt (O95243) Pfam (PF01429) | Homo sapiens (human) | Methyl-CpG-binding endonuclease 1, Methyl-CpG-binding protein MBD4, Mismatch-specific DNA N-glycosylase |
| 2 | B (B) | DNA (5'-D(*GP*GP*AP*TP*(5CM)P*GP*GP*CP*TP*C)-3') | polymer | 10 | 3075.0 | 1 | |||
| 3 | C (C) | DNA (5'-D(*GP*AP*GP*CP*(5CM)P*GP*AP*TP*CP*C)-3') | polymer | 10 | 3044.0 | 1 |
Sequence modifications
A: 80 - 148 (UniProt: O95243)
| PDB | External Database | Details |
|---|---|---|
| Gly 78 | - | expression tag |
| Ser 79 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 14207.3 | |
| All* | Total formula weight | 14207.3 |
