2MLF
NMR structure of the dilated cardiomyopathy mutation G159D in troponin C bound to the anchoring region of troponin I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Troponin C, slow skeletal and cardiac muscles | polymer | 72 | 8427.2 | 1 | UniProt (P63316) Pfam (PF13499) | Homo sapiens (human) | TN-C |
| 2 | B, C (C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
C: 91 - 161 (UniProt: P63316)
| PDB | External Database | Details |
|---|---|---|
| Met 90 | - | initiating methionine |
| Asp 159 | Gly 159 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 8427.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 8507.4 |
