2M9Y

Solution Structure of the Catalytic Domain of HHARI

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	E3 ubiquitin-protein ligase ARIH1	polymer	74	8439.3	1	UniProt (Q9Y4X5) Pfam (PF22191) In PDB	Homo sapiens (human)	H7-AP2, HHARI, Monocyte protein 6, MOP-6, Protein ariadne-1 homolog, ARI-1, UbcH7-binding protein, UbcM4-interacting protein, Ubiquitin-conjugating enzyme E2-binding protein 1
2	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A: 325 - 396 (UniProt: Q9Y4X5)

PDB	External Database	Details
Gly 323	-	expression tag
Ser 324	-	expression tag
Ser 357	Cys 357	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	8439.3
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	8570.1

*Water molecules are not included.