2M68
NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R in complex with IGF2 (domain 11 structure only)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Insulin-like growth factor 2 receptor variant | polymer | 142 | 15433.6 | 1 | UniProt (Q59EZ3) Pfam (PF00878) UniProt (by SIFTS) (P11717) In PDB | Homo sapiens (human) |
Sequence modifications
A: 1508 - 1649 (UniProt: Q59EZ3)
| PDB | External Database | Details |
|---|---|---|
| Ala 1543 | Ser 1466 | engineered mutation |
| Lys 1544 | Glu 1467 | engineered mutation |
| Gly 1545 | Lys 1468 | engineered mutation |
| Trp 1546 | Gly 1469 | engineered mutation |
| Gly 1547 | Leu 1470 | engineered mutation |
| Leu 1648 | Gln 1571 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15433.6 | |
| All* | Total formula weight | 15433.6 |
