2M5Q
Solution structure of lipidated glucagon analog in d-TFE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Glucagon | polymer | 30 | 3446.8 | 1 | UniProt (P01275) Pfam (PF00123) In PDB | Homo sapiens | |
| 2 | X | GAMMA-L-GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GGL) | |||
| 3 | X | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) |
Sequence modifications
X: 1 - 29 (UniProt: P01275)
| PDB | External Database | Details |
|---|---|---|
| Aib 2 | Ser 54 | engineered mutation |
| Lys 13 | Tyr 65 | engineered mutation |
| Aib 16 | Ser 68 | engineered mutation |
| Nh2 30 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 3446.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 550.7 | |
| All* | Total formula weight | 3997.5 |
