2M50
Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mu-theraphotoxin-Hh2a | polymer | 35 | 4062.8 | 1 | UniProt (P83303) Pfam (PF07740) | Haplopelma schmidti (Chinese bird spider Chinese golden earth tiger) | Mu-TRTX-Hh2a, Huwentoxin-4, Huwentoxin-IV, HwTx-IV, Huwentoxin-IVa, HWTX-IVa, Huwentoxin-IVb, HWTX-IVb, Huwentoxin-IVc, HWTX-IVc |
Sequence modifications
A: 1 - 35 (UniProt: P83303)
| PDB | External Database | Details |
|---|---|---|
| Ala 32 | Lys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 4062.8 | |
| All* | Total formula weight | 4062.8 |
