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2M50

Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMu-theraphotoxin-Hh2apolymer354062.81UniProt (P83303)
Pfam (PF07740)
In PDB
Haplopelma schmidti (Chinese bird spider Chinese golden earth tiger)Mu-TRTX-Hh2a, Huwentoxin-4, Huwentoxin-IV, HwTx-IV, Huwentoxin-IVa, HWTX-IVa, Huwentoxin-IVb, HWTX-IVb, Huwentoxin-IVc, HWTX-IVc
Sequence modifications
A: 1 - 35 (UniProt: P83303)
PDBExternal DatabaseDetails
Ala 32Lys 84engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight4062.8
All*Total formula weight4062.8
*Water molecules are not included.

217705

PDB entries from 2024-03-27

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