2M49
Structural Insights into Human S100B and Basic Fibroblast Growth Factor (FGF2) Interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Fibroblast growth factor 2 | polymer | 126 | 14422.5 | 2 | UniProt (P09038) Pfam (PF00167) In PDB | Homo sapiens (human) | FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2 |
| 2 | B, D | Protein S100-B | polymer | 91 | 10595.8 | 2 | UniProt (P04271) Pfam (PF01023) Pfam (PF00036) In PDB | Homo sapiens (human) | S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B |
Sequence modifications
A, C: 19 - 144 (UniProt: P09038)
| PDB | External Database | Details |
|---|---|---|
| Ser 69 | Cys 211 | engineered mutation |
| Ser 87 | Cys 229 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 50036.7 | |
| All* | Total formula weight | 50036.7 |
