2M1K

Interaction of Human S100A6 (C3S) with V domain of Receptor for Advanced Glycation End products (RAGE)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D	Protein S100-A6	polymer	90	10177.7	2	UniProt (P06703) Pfam (PF01023) In PDB	Homo sapiens (human)	Calcyclin, Growth factor-inducible protein 2A9, MLN 4, Prolactin receptor-associated protein, PRA, S100 calcium-binding protein A6
2	A, C	Advanced glycosylation end product-specific receptor	polymer	101	11217.0	2	UniProt (Q15109) Pfam (PF00047) In PDB	Homo sapiens (human)	Receptor for advanced glycosylation end products

Sequence modifications

B, D: 1 - 90 (UniProt: P06703)

PDB	External Database	Details
Ser 3	Cys 3	engineered mutation

A, C: 23 - 121 (UniProt: Q15109)

PDB	External Database	Details
Ala 21	-	expression tag
Met 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	42789.3
All*	Total formula weight	42789.3

*Water molecules are not included.