2LWI
Solution structure of H-RasT35S mutant protein in complex with Kobe2601
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | GTPase HRas | polymer | 172 | 19387.7 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (human) | H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras, GTPase HRas, N-terminally processed |
| 2 | A | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | 2-(2,4-dinitrophenyl)-N-(4-fluorophenyl)hydrazinecarbothioamide | non-polymer | 351.3 | 1 | Chemie (KOB) | |||
| 5 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Ser 35 | Thr 35 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19387.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 897.8 | |
| All* | Total formula weight | 20285.5 |
