2L7M
Solution Structure of the Pitx2 Homeodomain R24H mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | P | Pituitary homeobox 2 | polymer | 68 | 8467.5 | 1 | UniProt (Q99697) Pfam (PF00046) In PDB | Homo sapiens (Human) | ALL1-responsive protein ARP1 Homeobox protein PITX2, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor, Solurshin |
Sequence modifications
P: 1 - 60 (UniProt: Q99697)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| His 24 | Arg 108 | engineered mutation |
| Glu 61 | - | SEE REMARK 999 |
| Phe 62 | - | SEE REMARK 999 |
| Ile 63 | - | SEE REMARK 999 |
| Val 64 | - | SEE REMARK 999 |
| Thr 65 | - | SEE REMARK 999 |
| Asp 66 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 8467.5 | |
| All* | Total formula weight | 8467.5 |
