2L74

Solution structure of the PilZ domain protein PA4608 complex with c-di-GMP identifies charge clustering as molecular readout

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Putative uncharacterized protein PA4608	polymer	145	16764.7	1	UniProt (Q9HVI1) Pfam (PF07238)	Pseudomonas aeruginosa
2	B, C (A)	9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)	non-polymer		690.4	2	Chemie (C2E) PubChem (135440063) PubChem (135566344) PubChem (136437725) PubChem (136465801) PubChem (136503951) PubChem (146177770) PubChem (173716374) PubChem (174009991) PubChem (135566464) PubChem (135625254) PubChem (135867623) PubChem (135975628) PubChem (136177399) PubChem (136443483) PubChem (137221491) PubChem (137295286) PubChem (148921766) PubChem (148921769) PubChem (164708340) PubChem (168270823)

Sequence modifications

A: 1 - 125 (UniProt: Q9HVI1)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16764.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1380.8
All*	Total formula weight	18145.6

*Water molecules are not included.