2L74
Solution structure of the PilZ domain protein PA4608 complex with c-di-GMP identifies charge clustering as molecular readout
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE C2E A 501 |
| Chain | Residue |
| A | ARG8 |
| A | ILE41 |
| A | LEU42 |
| A | TRP77 |
| A | PHE85 |
| A | GLU86 |
| A | C2E502 |
| A | ARG9 |
| A | ARG10 |
| A | ARG13 |
| A | ASP35 |
| A | VAL36 |
| A | SER37 |
| A | HIS39 |
| A | GLY40 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE C2E A 502 |
| Chain | Residue |
| A | HIS5 |
| A | ASP6 |
| A | GLU7 |
| A | ARG8 |
| A | ARG9 |
| A | HIS12 |
| A | ARG13 |
| A | TRP77 |
| A | C2E501 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Domain: {"description":"PilZ","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"RXXXR motif; surrounds the surface of the c-di-GMP binding site","evidences":[{"source":"PubMed","id":"21280119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21310957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Motif: {"description":"DXSXXG motif; surrounds the surface of the c-di-GMP binding site","evidences":[{"source":"PubMed","id":"21280119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21310957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21310957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for c-di-GMP binding"} |
| Chain | Residue | Details |
