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2KS1

Heterodimeric association of Transmembrane domains of ErbB1 and ErbB2 receptors Enabling Kinase Activation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Receptor tyrosine-protein kinase erbB-2polymer444734.81UniProt (P04626)
Pfam (PF21314)
Homo sapiens (human)p185erbB2, C-erbB-2, NEU proto-oncogene, Tyrosine kinase-type cell surface receptor HER2, MLN 19
2B
(B)
Epidermal growth factor receptorpolymer444733.81UniProt (P00533)
Pfam (PF21314)
Homo sapiens (human)Receptor tyrosine-protein kinase ErbB-1
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight9468.7
All*Total formula weight9468.7
*Water molecules are not included.

236963

PDB entries from 2025-06-04

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