2KNC

Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Integrin alpha-IIb	polymer	54	6057.1	1	UniProt (P08514) Pfam (PF00357) In PDB	Homo sapiens (human)	Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2
2	B	Integrin beta-3	polymer	79	8775.3	1	UniProt (P05106) Pfam (PF08725) In PDB	Homo sapiens (human)	Platelet membrane glycoprotein IIIa, GPIIIa

Sequence modifications

A: 960 - 1008 (UniProt: P08514)

PDB	External Database	Details
Gly 955	-	expression tag
Ala 956	-	expression tag
Met 957	-	expression tag
Gly 958	-	expression tag
Ser 959	-	expression tag

B: 689 - 762 (UniProt: P05106)

PDB	External Database	Details
Gly 684	-	expression tag
Ala 685	-	expression tag
Met 686	-	expression tag
Gly 687	-	expression tag
Ser 688	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	14832.3
All*	Total formula weight	14832.3

*Water molecules are not included.