2KFX
Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | Troponin C, slow skeletal and cardiac muscles | polymer | 89 | 10038.2 | 1 | UniProt (P63316) Pfam (PF13833) | Homo sapiens (human) | TN-C |
| 2 | B (T) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (T) | N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE | non-polymer | 340.9 | 1 | Chemie (WW7) |
Sequence modifications
T: 1 - 89 (UniProt: P63316)
| PDB | External Database | Details |
|---|---|---|
| Ser 35 | Cys 35 | engineered mutation |
| Ser 84 | Cys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10038.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 380.9 | |
| All* | Total formula weight | 10419.1 |
