2KA6

NMR structure of the CBP-TAZ2/STAT1-TAD complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CREB-binding protein	polymer	92	10527.6	1	UniProt (P45481) Pfam (PF02135) In PDB	Mus musculus (mouse)
2	B	Signal transducer and activator of transcription 1-alpha/beta	polymer	45	5041.6	1	UniProt (P42224) Pfam (PF12162) In PDB	Homo sapiens (human)	Transcription factor ISGF-3 components p91/p84
3	A	ZINC ION	non-polymer		65.4	3	Chemie (ZN)

Sequence modifications

A: 1 - 92 (UniProt: P45481)

PDB	External Database	Details
Lys 87	Asn 1850	engineered mutation
Leu 88	Val 1851	engineered mutation

B: 710 - 750 (UniProt: P42224)

PDB	External Database	Details
Gly 706	-	expression tag
Ser 707	-	expression tag
His 708	-	expression tag
Met 709	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	15569.1
Non-Polymers*	Number of molecules	3
	Total formula weight	196.2
All*	Total formula weight	15765.4

*Water molecules are not included.