2KA6

NMR structure of the CBP-TAZ2/STAT1-TAD complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004402	molecular_function	histone acetyltransferase activity
A	0006355	biological_process	regulation of DNA-templated transcription
B	0003700	molecular_function	DNA-binding transcription factor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 93

Chain	Residue
A	HIS19
A	CYS23
A	ASN25

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 94

Chain	Residue
A	HIS42
A	THR43
A	CYS46
A	ARG48
A	LYS49

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 95

Chain	Residue
A	CYS71
A	HIS67

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Required for recruitment of EP300/p300 => ECO:0000269|PubMed:16257975

Chain	Residue	Details
B	LEU724

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by CAMK2 and MAPK14 => ECO:0000269|PubMed:11972023, ECO:0000269|PubMed:15322115, ECO:0000269|PubMed:16257975, ECO:0000269|PubMed:17897103, ECO:0000269|PubMed:21135090, ECO:0000269|PubMed:22065572, ECO:0000269|PubMed:26479788, ECO:0000269|PubMed:7543024, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	SER727

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by IKKE => ECO:0000250|UniProtKB:P42225

Chain	Residue	Details
B	SER745

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