2K42

Solution Structure of the GTPase Binding Domain of WASP in Complex with EspFU, an EHEC Effector

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Wiskott-Aldrich syndrome protein	polymer	72	8128.9	1	UniProt (P42768) Pfam (PF00786) In PDB	Homo sapiens (human)	WASp
2	B	ESPFU	polymer	36	4070.7	1	UniProt (Q8X2D5) In PDB	Escherichia coli O157:H7	Tir-cytoskeleton coupling protein

Sequence modifications

A: 4 - 72 (UniProt: P42768)

PDB	External Database	Details
Gly 1	-	expression tag
His 2	-	expression tag
Met 3	-	expression tag

B: 76 - 108 (UniProt: Q8X2D5)

PDB	External Database	Details
Gly 73	-	expression tag
His 74	-	expression tag
Met 75	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	12199.6
All*	Total formula weight	12199.6

*Water molecules are not included.