2K31
Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phosphodiesterase 5A, cGMP-specific | polymer | 176 | 19968.5 | 1 | UniProt (Q0VBW0) Pfam (PF01590) UniProt (by SIFTS) (Q8CG03) In PDB | Mus musculus (mouse) | |
2 | A | GUANOSINE-3',5'-MONOPHOSPHATE | non-polymer | 345.2 | 1 | Chemie (35G) |
Sequence modifications
A: 154 - 320 (UniProt: Q0VBW0)
PDB | External Database | Details |
---|---|---|
Met 153 | - | initiating methionine |
Glu 295 | Ala 295 | engineered mutation |
Glu 302 | Ile 302 | engineered mutation |
Leu 321 | - | expression tag |
Glu 322 | - | expression tag |
His 323 | - | expression tag |
His 324 | - | expression tag |
His 325 | - | expression tag |
His 326 | - | expression tag |
His 327 | - | expression tag |
His 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19968.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 345.2 | |
All* | Total formula weight | 20313.7 |