2K2U
NMR Structure of the complex between Tfb1 subunit of TFIIH and the activation domain of VP16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA polymerase II transcription factor B subunit 1 | polymer | 115 | 12903.7 | 1 | UniProt (P32776) Pfam (PF08567) | Saccharomyces cerevisiae (Baker's yeast) | RNA polymerase II transcription factor B p73 subunit, RNA polymerase II transcription factor B 73 kDa subunit, General transcription and DNA repair factor IIH subunit TFB1, TFIIH subunit TFB1 |
| 2 | B (B) | Alpha trans-inducing protein | polymer | 35 | 3817.1 | 1 | UniProt (P04486) Pfam (PF12149) | Human herpesvirus 1 (HHV-1) | Vmw65, ICP25, VP16 protein, Alpha-TIF |
Sequence modifications
A: 1 - 115 (UniProt: P32776)
| PDB | External Database | Details |
|---|---|---|
| Pro 1 | Met 1 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16720.8 | |
| All* | Total formula weight | 16720.8 |
