2JLY

Dengue virus 4 NS3 helicase in complex with ssRNA and ADP-Phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	SERINE PROTEASE SUBUNIT NS3	polymer	451	51337.5	2	UniProt (Q2YHF0) Pfam (PF07652) Pfam (PF20907)	DENGUE VIRUS 4	DENV4 NS3 HELICASE, NON-STRUCTURAL PROTEIN 3
2	C, D (C, D)	5'-R(*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3'	polymer	12	3803.4	2
3	E, I (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
4	F, J (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
5	G, K (A, B)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
6	H, L (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	M, N, O, P (A, B, C, D)	water	water		18.0	380	Chemie (HOH)

Sequence modifications

A, B: 168 - 171 (PDB: 2JLY)
A, B: 172 - 618 (UniProt: Q2YHF0)

PDB	External Database	Details
Leu 213	Lys 1687	conflict
Asp 250	Glu 1724	conflict
Cys 292	Ser 1766	conflict
Ser 321	Thr 1795	conflict
Arg 381	Lys 1855	conflict
Lys 480	Arg 1954	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110281.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1338.4
All*	Total formula weight	111620.0

*Water molecules are not included.