2JLW

Dengue virus 4 NS3 helicase in complex with ssRNA2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	SERINE PROTEASE SUBUNIT NS3	polymer	451	51365.5	2	UniProt (Q2YHF0) Pfam (PF07652) Pfam (PF20907)	DENGUE VIRUS 4	DENV4 NS3 HELICASE, NON-STRUCTURAL PROTEIN 3
2	C, D (C, D)	5'-R(*UP*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3'	polymer	13	4109.5	2
3	E, G (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	F (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	H, I, J (A, B, C)	water	water		18.0	129	Chemie (HOH)

Sequence modifications

A, B: 168 - 171 (PDB: 2JLW)
A, B: 172 - 618 (UniProt: Q2YHF0)

PDB	External Database	Details
Asp 250	Glu 1724	conflict
Cys 292	Ser 1766	conflict
Ser 321	Thr 1795	conflict
Ile 322	Thr 1796	conflict
Arg 381	Lys 1855	conflict
Lys 480	Arg 1954	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110950.1
Non-Polymers*	Number of molecules	3
	Total formula weight	282.0
All*	Total formula weight	111232.1

*Water molecules are not included.