2JLS
Dengue virus 4 NS3 helicase in complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE PROTEASE SUBUNIT NS3 | polymer | 451 | 51353.5 | 1 | UniProt (Q2YHF0) Pfam (PF07652) Pfam (PF20907) | DENGUE VIRUS 4 | DENV4 NS3 HELICASE, NON-STRUCTURAL PROTEIN 3 |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D, E (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | H (A) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A: 168 - 171 (PDB: 2JLS)
A: 172 - 618 (UniProt: Q2YHF0)
A: 172 - 618 (UniProt: Q2YHF0)
| PDB | External Database | Details |
|---|---|---|
| Asp 250 | Glu 1724 | conflict |
| Cys 292 | Ser 1766 | conflict |
| Ser 321 | Thr 1795 | conflict |
| Arg 381 | Lys 1855 | conflict |
| Lys 480 | Arg 1954 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51353.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 766.0 | |
| All* | Total formula weight | 52119.4 |
