2JLG
STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA-DEPENDENT RNA POLYMERASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | RNA-DIRECTED RNA POLYMERASE | polymer | 664 | 74902.2 | 3 | UniProt (P11124) Pfam (PF00680) | PSEUDOMONAS PHAGE PHI6 | PROTEIN P2 |
| 2 | D, E, F (D, E, F) | 5'-D(*DT DT DT DC DCP)-3' | polymer | 5 | 1446.0 | 3 | PSEUDOMONAS PHAGE PHI6 | ||
| 3 | G, H, I, J (A, B, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 4 | K (C) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) PubChem (27854) |
Sequence modifications
A, B, C: 1 - 664 (UniProt: P11124)
| PDB | External Database | Details |
|---|---|---|
| Met 456 | Ile 457 | conflict |
| Gln 491 | Glu 492 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 229044.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2147.7 | |
| All* | Total formula weight | 231192.3 |
