2JFL
CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (DIPHOSPHORYLATED FORM) BOUND TO 5- AMINO-3-((4-(AMINOSULFONYL)PHENYL)AMINO)-N-(2,6- DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | STE20-LIKE SERINE/THREONINE-PROTEIN KINASE | polymer | 325 | 37322.0 | 1 | UniProt (Q9H2G2) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | STE20-LIKE SERINE-THREONINE KINASE, STE20-LIKE KINASE, STE20-RELATED SERINE/THREONINE-PROTEIN KINASE, STE20-RELATED KINASE, HSLK, SERINE/THREONINE-PROTEIN KINASE 2, CTCL TUMOR ANTIGEN SE20-9 |
| 2 | A | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE | non-polymer | 425.4 | 1 | Chemie (DKI) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | A | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37322.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 829.3 | |
| All* | Total formula weight | 38151.3 |
