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2JF9

ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
ESTROGEN RECEPTORpolymer25228672.53UniProt (P03372)
Pfam (PF00104)
HOMO SAPIENS (HUMAN)ER, ESTRADIOL RECEPTOR, ER-ALPHA, ESTROGEN RECEPTOR ALPHA
2D, E, F
(P, Q, R)
AB5 PEPTIDEpolymer131541.73SYNTHETIC CONSTRUCT
3G, K, N
(A, B, C)
4-HYDROXYTAMOXIFENnon-polymer387.53Chemie (OHT)
4H
(A)
BICARBONATE IONnon-polymer61.01Chemie (BCT)
5I, J, L, M, O...
(A, B, C)
1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
6Q, R
(P, R)
CALCIUM IONnon-polymer40.12Chemie (CA)
7S, T, U, V, W...
(A, B, C, P, Q...)
waterwater18.0296Chemie (HOH)
Sequence modifications
A, B, C: 282 - 303 (PDB: 2JF9)
A, B, C: 304 - 533 (UniProt: P03372)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight90642.8
Non-Polymers*Number of molecules12
Total formula weight1676.1
All*Total formula weight92318.9
*Water molecules are not included.

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PDB entries from 2025-12-10

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