2JF9
ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BCT A 700 |
| Chain | Residue |
| A | LEU327 |
| A | TYR328 |
| A | ARG352 |
| C | ILE326 |
| C | LEU327 |
| C | TYR328 |
| C | ARG352 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA P 1014 |
| Chain | Residue |
| P | ASP10 |
| P | SER13 |
| C | THR334 |
| C | HOH2021 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA R 1014 |
| Chain | Residue |
| A | THR334 |
| A | HOH2018 |
| R | ASP10 |
| R | SER13 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE OHT A 600 |
| Chain | Residue |
| A | MET343 |
| A | LEU346 |
| A | THR347 |
| A | ALA350 |
| A | ASP351 |
| A | GLU353 |
| A | TRP383 |
| A | LEU384 |
| A | ARG394 |
| A | PHE404 |
| A | MET421 |
| A | LEU428 |
| A | GLY521 |
| A | HIS524 |
| A | LEU525 |
| P | PRO2 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1529 |
| Chain | Residue |
| A | TYR331 |
| A | PRO333 |
| A | ASN407 |
| A | HOH2095 |
| C | ASN359 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1530 |
| Chain | Residue |
| A | GLU323 |
| A | TRP393 |
| A | GLY442 |
| A | HOH2096 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE OHT B 600 |
| Chain | Residue |
| B | MET343 |
| B | LEU346 |
| B | THR347 |
| B | ALA350 |
| B | ASP351 |
| B | GLU353 |
| B | LEU384 |
| B | ARG394 |
| B | PHE404 |
| B | MET421 |
| B | LEU428 |
| B | GLY521 |
| Q | PRO2 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1530 |
| Chain | Residue |
| A | TYR459 |
| B | MET427 |
| B | THR431 |
| B | HIS513 |
| B | HIS516 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1531 |
| Chain | Residue |
| B | LEU320 |
| B | GLU323 |
| B | TRP393 |
| B | GLY442 |
| site_id | BC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE OHT C 600 |
| Chain | Residue |
| C | MET343 |
| C | LEU346 |
| C | ALA350 |
| C | ASP351 |
| C | GLU353 |
| C | ARG394 |
| C | MET421 |
| C | ILE424 |
| C | LEU428 |
| C | HIS524 |
| C | LEU525 |
| R | SER1 |
| R | PRO2 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 1530 |
| Chain | Residue |
| A | VAL355 |
| A | ASN359 |
| C | TYR331 |
| C | ASN407 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 1531 |
| Chain | Residue |
| C | LEU320 |
| C | GLU323 |
| C | TRP393 |
| C | GLY442 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9338790","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9600906","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ERE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
