2JDO
STRUCTURE OF PKB-BETA (AKT2) COMPLEXED WITH ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY) ETHYLAMINO)ETHYL)AMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RAC-BETA SERINE/THREONINE-PROTEIN KINASE | polymer | 342 | 39860.4 | 1 | UniProt (P31751) Pfam (PF00069) Pfam (PF00433) | HOMO SAPIENS (HUMAN) | PROTEIN KINASE B-BETA, RAC-PK-BETA, PROTEIN KINASE AKT-2, PROTEIN KINASE B, BETA, PKB BETA |
| 2 | B (C) | GLYCOGEN SYNTHASE KINASE-3 BETA | polymer | 10 | 1123.2 | 1 | UniProt (P49841) | HOMO SAPIENS | GSK3-BETA PEPTIDE, GSK-3 BETA |
| 3 | C (A) | ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE | non-polymer | 419.9 | 1 | Chemie (I5S) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E, F (A, C) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40983.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 482.0 | |
| All* | Total formula weight | 41465.6 |
