2JCC

AH3 recognition of mutant HLA-A2 W167A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, H	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN	polymer	275	31739.1	2	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB	HOMO SAPIENS (HUMAN)	MHC CLASS I ANTIGEN A*2, HLA-A2
2	B, I	BETA-2-MICROGLOBULIN	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654) In PDB	HOMO SAPIENS (HUMAN)	B2M
3	C, J	P1049	polymer	9	1049.3	2	UniProt (by SIFTS) (Q9NPA0) In PDB	HOMO SAPIENS
4	E, L	TCR ALPHA	polymer	194	21656.3	2	Pfam (PF09291) UniProt (by SIFTS) (P01849) In PDB	MUS MUSCULUS (MOUSE)
5	F, M	TCR BETA	polymer	238	26890.9	2		MUS MUSCULUS (MOUSE)
6		water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, H: 1 - 275 (UniProt: P01892)

PDB	External Database	Details
Ala 167	Trp 191	engineered mutation

B, I: 0 - 0 (PDB: 2JCC)
B, I: 1 - 99 (UniProt: P61769)

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	186429.8
All*	Total formula weight	186429.8

*Water molecules are not included.