2JCC
AH3 recognition of mutant HLA-A2 W167A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, H) | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN | polymer | 275 | 31739.1 | 2 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | HOMO SAPIENS (HUMAN) | MHC CLASS I ANTIGEN A*2, HLA-A2 |
| 2 | B, G (B, I) | BETA-2-MICROGLOBULIN | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | HOMO SAPIENS (HUMAN) | B2M |
| 3 | C, H (C, J) | P1049 | polymer | 9 | 1049.3 | 2 | UniProt (by SIFTS) (Q9NPA0) | HOMO SAPIENS | |
| 4 | D, I (E, L) | TCR ALPHA | polymer | 194 | 21656.3 | 2 | Pfam (PF09291) UniProt (by SIFTS) (P01849) | MUS MUSCULUS (MOUSE) | |
| 5 | E, J (F, M) | TCR BETA | polymer | 238 | 26890.9 | 2 | MUS MUSCULUS (MOUSE) | ||
| 6 | K, L, M, N, O... (A, B, E, F, H...) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A, H: 1 - 275 (UniProt: P01892)
B, I: 0 - 0 (PDB: 2JCC)
B, I: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Ala 167 | Trp 191 | engineered mutation |
B, I: 1 - 99 (UniProt: P61769)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 186429.8 | |
| All* | Total formula weight | 186429.8 |
