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2JBP

Protein kinase MK2 in complex with an inhibitor (crystal form-2, co- crystallization)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...MAP KINASE-ACTIVATED PROTEIN KINASE 2polymer32637665.512UniProt (P49137)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)MAPKAP KINASE 2, MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAPK-2, MK2
2A, B, C, D, E...2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONEnon-polymer340.411Chemie (P4O)
3waterwater18.018Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 39 - 40 (PDB: 2JBP)
A, B, C, D, E, F, G, H, I, J, K, L: 41 - 364 (UniProt: P49137)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight451985.5
Non-Polymers*Number of molecules11
Total formula weight3744.2
All*Total formula weight455729.7
*Water molecules are not included.

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PDB entries from 2024-04-24

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