2JBP
Protein kinase MK2 in complex with an inhibitor (crystal form-2, co- crystallization)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | MAP KINASE-ACTIVATED PROTEIN KINASE 2 | polymer | 326 | 37665.5 | 12 | UniProt (P49137) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | MAPKAP KINASE 2, MAPK-ACTIVATED PROTEIN KINASE 2, MAPKAPK-2, MK2 |
2 | A, B, C, D, E... | 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE | non-polymer | 340.4 | 11 | Chemie (P4O) | |||
3 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 39 - 40 (PDB: 2JBP)
A, B, C, D, E, F, G, H, I, J, K, L: 41 - 364 (UniProt: P49137)
A, B, C, D, E, F, G, H, I, J, K, L: 41 - 364 (UniProt: P49137)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 451985.5 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 3744.2 | |
All* | Total formula weight | 455729.7 |