2J4A
Human Thyroid hormone receptor beta ligand binding domain in complex with KB131084
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYROID HORMONE RECEPTOR BETA-1 | polymer | 253 | 28555.1 | 1 | UniProt (P10828) Pfam (PF00104) | HOMO SAPIENS (HUMAN) | THYROID HORMONE RECEPTOR BETA LBD |
| 2 | B (A) | 3,5-DIBROMO-4-(3-ISOPROPYL-PHENOXY)BENZOIC ACID | non-polymer | 458.1 | 1 | Chemie (OEF) | |||
| 3 | C (A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 209 - 461 (UniProt: P10828)
| PDB | External Database | Details |
|---|---|---|
| Ser 331 | Asn 331 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28555.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 458.1 | |
| All* | Total formula weight | 29013.2 |
