2J4A
Human Thyroid hormone receptor beta ligand binding domain in complex with KB131084
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | EMBL/DESY, HAMBURG BEAMLINE BW7A |
Synchrotron site | EMBL/DESY, HAMBURG |
Beamline | BW7A |
Temperature [K] | 100 |
Spacegroup name | C 2 2 21 |
Unit cell lengths | 77.212, 107.422, 67.208 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 40.000 - 2.200 |
R-factor | 0.2297 |
Rwork | 0.230 |
R-free | 0.27290 |
Structure solution method | OTHER |
RMSD bond length | 0.000 |
RMSD bond angle | 0.000 |
Refinement software | CNS |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 20.000 |
High resolution limit [Å] | 2.200 |
Rmerge | 0.110 |
Number of reflections | 14513 |
<I/σ(I)> | 7.7 |
Completeness [%] | 99.9 |
Redundancy | 5.1 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | 0.45 M AMMONIUMSULFATE, 100 MMTRIS PH8.0, 100MM NDSB |