2J0S
The crystal structure of the Exon Junction Complex at 2.2 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-DEPENDENT RNA HELICASE DDX48 | polymer | 410 | 46799.8 | 1 | UniProt (P38919) Pfam (PF00270) Pfam (PF00271) | HOMO SAPIENS (HUMAN) | EIF4AIII RNA-HELICASE, DEAD BOX PROTEIN 48, EUKARYOTIC INITIATION FACTOR 4A-LIKE NUK-34, NUCLEAR MATRIX PROTEIN 265, HNMP 265, EUKARYOTIC TRANSLATION INITIATION FACTOR 4A ISOFORM 3 |
| 2 | B (C) | PROTEIN MAGO NASHI HOMOLOG | polymer | 146 | 17189.6 | 1 | UniProt (P61326) Pfam (PF02792) | HOMO SAPIENS (HUMAN) | |
| 3 | C (D) | RNA-BINDING PROTEIN 8A | polymer | 89 | 10216.4 | 1 | UniProt (Q9Y5S9) Pfam (PF00076) | HOMO SAPIENS (HUMAN) | RNA-BINDING MOTIF PROTEIN 8A, RIBONUCLEOPROTEIN RBM8A, RNA-BINDING PROTEIN Y14, BINDER OF OVCA1-1, BOV-1 |
| 4 | D (E) | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3' | polymer | 15 | 4547.5 | 1 | |||
| 5 | E (T) | PROTEIN CASC3 | polymer | 150 | 17713.5 | 1 | UniProt (O15234) Pfam (PF09405) | HOMO SAPIENS (HUMAN) | BARENTSZ, CANCER SUSCEPTIBILITY CANDIDATE GENE 3 PROTEIN, METASTATIC LYMPH NODE PROTEIN 51, BTZ, MLN 51 PROTEIN, BARENTSZ PROTEIN |
| 6 | F (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | G (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 8 | H, I, J, K, L (A, C, D, E, T) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 96466.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 96997.3 |
