2J0Q
The crystal structure of the Exon Junction Complex at 3.2 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ATP-DEPENDENT RNA HELICASE DDX48 | polymer | 410 | 46799.8 | 2 | UniProt (P38919) Pfam (PF00270) Pfam (PF00271) | HOMO SAPIENS (HUMAN) | EIF4AIII RNA-HELICASE, DEAD BOX PROTEIN 48, EUKARYOTIC INITIATION FACTOR 4A-LIKE NUK-34, HNMP 265, NUCLEAR MATRIX PROTEIN 265, EUKARYOTIC TRANSLATION INITIATION FACTOR 4A ISOFORM 3 |
| 2 | C, F (C, F) | PROTEIN MAGO NASHI HOMOLOG | polymer | 146 | 17189.6 | 2 | UniProt (P61326) Pfam (PF02792) | HOMO SAPIENS (HUMAN) | MGN |
| 3 | D, G (D, G) | RNA-BINDING PROTEIN 8A | polymer | 109 | 12701.3 | 2 | UniProt (Q9Y5S9) Pfam (PF00076) | HOMO SAPIENS (HUMAN) | Y14, RNA-BINDING MOTIF PROTEIN 8A, RIBONUCLEOPROTEIN RBM8A, RNA-BINDING PROTEIN Y14, BINDER OF OVCA1-1, BOV-1 |
| 4 | E, H (E, H) | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3' | polymer | 15 | 4547.5 | 2 | |||
| 5 | I, J (I, T) | PROTEIN CASC3 | polymer | 150 | 17713.5 | 2 | UniProt (O15234) Pfam (PF09405) | HOMO SAPIENS (HUMAN) | BARENTSZ, CANCER SUSCEPTIBILITY CANDIDATE GENE 3 PROTEIN, METASTATIC LYMPH NODE PROTEIN 51 MLN 51 PROTEIN BARENTSZ PROTEIN, BTZ |
| 6 | K, M (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | L, N (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 8 | O (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 197903.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1061.0 | |
| All* | Total formula weight | 198964.4 |
