2J0M

Crystal structure a two-chain complex between the FERM and kinase domains of focal adhesion kinase.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	FOCAL ADHESION KINASE 1	polymer	371	42444.2	1	UniProt (Q00944) Pfam (PF18038) Pfam (PF00373) Pfam (PF21477) In PDB	GALLUS GALLUS (CHICKEN)	FOCAL ADHESION KINASE, FADK 1, PP125FAK
2	B	FOCAL ADHESION KINASE 1	polymer	276	31758.8	1	UniProt (Q00944) Pfam (PF07714) In PDB	GALLUS GALLUS (CHICKEN)	FOCAL ADHESION KINASE, FADK 1, PP125FAK
3	B	1,2,3,4-TETRAHYDROGEN-STAUROSPORINE	non-polymer		470.6	1	Chemie (4ST)
4		water	water		18.0	53	Chemie (HOH)

Sequence modifications

A: 29 - 30 (PDB: 2J0M)
A: 31 - 399 (UniProt: Q00944)
B: 411 - 686 (UniProt: Q00944)

PDB	External Database	Details
Leu 449	Met 449	conflict
Tyr 516	Phe 516	conflict
Ser 556	Ala 556	conflict
Asn 557	Thr 557	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74203.0
Non-Polymers*	Number of molecules	1
	Total formula weight	470.6
All*	Total formula weight	74673.6

*Water molecules are not included.