2J0M
Crystal structure a two-chain complex between the FERM and kinase domains of focal adhesion kinase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FOCAL ADHESION KINASE 1 | polymer | 371 | 42444.2 | 1 | UniProt (Q00944) Pfam (PF18038) Pfam (PF00373) Pfam (PF21477) | GALLUS GALLUS (CHICKEN) | FOCAL ADHESION KINASE, FADK 1, PP125FAK |
| 2 | B (B) | FOCAL ADHESION KINASE 1 | polymer | 276 | 31758.8 | 1 | UniProt (Q00944) Pfam (PF07714) | GALLUS GALLUS (CHICKEN) | FOCAL ADHESION KINASE, FADK 1, PP125FAK |
| 3 | C (B) | 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE | non-polymer | 470.6 | 1 | Chemie (4ST) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 29 - 30 (PDB: 2J0M)
A: 31 - 399 (UniProt: Q00944)
B: 411 - 686 (UniProt: Q00944)
A: 31 - 399 (UniProt: Q00944)
B: 411 - 686 (UniProt: Q00944)
| PDB | External Database | Details |
|---|---|---|
| Leu 449 | Met 449 | conflict |
| Tyr 516 | Phe 516 | conflict |
| Ser 556 | Ala 556 | conflict |
| Asn 557 | Thr 557 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74203.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 470.6 | |
| All* | Total formula weight | 74673.6 |
