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2J0L

Crystal structure of a the active conformation of the kinase domain of focal adhesion kinase with a phosphorylated activation loop.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
FOCAL ADHESION KINASE 1polymer27631920.81UniProt (Q00944)
Pfam (PF07714)
GALLUS GALLUS (CHICKEN)FADK 1, PP125FAK
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
5E
(A)
waterwater18.097Chemie (HOH)
Sequence modifications
A: 411 - 686 (UniProt: Q00944)
PDBExternal DatabaseDetails
Ser 556Ala 556conflict
Asn 557Thr 557conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31920.8
Non-Polymers*Number of molecules3
Total formula weight626.6
All*Total formula weight32547.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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