2J0L
Crystal structure of a the active conformation of the kinase domain of focal adhesion kinase with a phosphorylated activation loop.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | FOCAL ADHESION KINASE 1 | polymer | 276 | 31920.8 | 1 | UniProt (Q00944) Pfam (PF07714) In PDB | GALLUS GALLUS (CHICKEN) | FADK 1, PP125FAK |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 411 - 686 (UniProt: Q00944)
| PDB | External Database | Details |
|---|---|---|
| Ser 556 | Ala 556 | conflict |
| Asn 557 | Thr 557 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31920.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 626.6 | |
| All* | Total formula weight | 32547.3 |
