2IZR
Structure of casein kinase gamma 3 in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CASEIN KINASE I ISOFORM GAMMA-3 | polymer | 330 | 38557.4 | 1 | UniProt (Q9Y6M4) Pfam (PF00069) Pfam (PF12605) | HOMO SAPIENS (HUMAN) | CKI-GAMMA 3, CASEIN KINASE 1 GAMMA 3 |
| 2 | B (A) | {(2Z)-4-AMINO-2-[(4-METHOXYPHENYL)IMINO]-2,3-DIHYDRO-1,3-THIAZOL-5-YL}(4-METHOXYPHENYL)METHANONE | non-polymer | 355.4 | 1 | Chemie (BRK) | |||
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, F, G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | I (A) | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 1 | Chemie (PGO) | |||
| 6 | J (A) | water | water | 18.0 | 474 | Chemie (HOH) |
Sequence modifications
A: 33 - 34 (PDB: 2IZR)
A: 35 - 362 (UniProt: Q9Y6M4)
A: 35 - 362 (UniProt: Q9Y6M4)
| PDB | External Database | Details |
|---|---|---|
| Ala 187 | Gly 187 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38557.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 621.9 | |
| All* | Total formula weight | 39179.3 |
