2IXG

Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ANTIGEN PEPTIDE TRANSPORTER 1	polymer	271	29508.5	1	UniProt (P36370) Pfam (PF00005)	RATTUS NORVEGICUS (RAT)	TAP1, APT1, PEPTIDE TRANSPORTER TAP1, ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 2
2	B (A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	D (A)	water	water		18.0	45	Chemie (HOH)

Sequence modifications

A: 464 - 464 (PDB: 2IXG)
A: 726 - 734 (PDB: 2IXG)
A: 465 - 725 (UniProt: P36370)

PDB	External Database	Details
Ala 621	Ser 621	engineered mutation
Val 622	Gly 622	engineered mutation
Asn 645	Asp 645	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29508.5
Non-Polymers*	Number of molecules	2
	Total formula weight	599.3
All*	Total formula weight	30107.8

*Water molecules are not included.