2IXG

Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ATP A 1

Chain	Residue
A	TYR489
A	THR523
A	GLN678
A	VAL497
A	PRO516
A	ASN517
A	GLY518
A	SER519
A	GLY520
A	LYS521
A	SER522

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 2

Chain	Residue
A	HIS555
A	ALA560
A	ARG632
A	ARG636
A	ARG660
A	HOH2021

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Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LAVGQRQAVALARAL

Chain	Residue	Details
A	LEU620-LEU634

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	239
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17018292","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2IXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IXF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K8O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17018292","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25377891","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2IXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IXF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K8O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17018292","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25377891","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2IXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K8O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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