2IXF

Crystal structure of the ATPase domain of TAP1 with ATP (D645Q, Q678H mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	ANTIGEN PEPTIDE TRANSPORTER 1	polymer	271	29506.5	4	UniProt (P36370) Pfam (PF00005) In PDB	RATTUS NORVEGICUS (RAT)	TAP1, APT1, PEPTIDE TRANSPORTER TAP1, ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 2
2	A, B, C, D	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	4	Chemie (ATP)
3	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	A, B, C, D	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
5		water	water		18.0	968	Chemie (HOH)

Sequence modifications

A, B, C, D: 465 - 725 (UniProt: P36370)

PDB	External Database	Details
Met 464	-	expression tag
Ala 726	-	expression tag
Ala 727	-	expression tag
Ala 728	-	expression tag
His 729	-	expression tag
His 730	-	expression tag
His 731	-	expression tag
His 732	-	expression tag
His 733	-	expression tag
His 734	-	expression tag
Gln 645	Asp 645	engineered mutation
His 678	Gln 678	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	118025.9
Non-Polymers*	Number of molecules	13
	Total formula weight	2586.4
All*	Total formula weight	120612.4

*Water molecules are not included.