2IVT

Crystal structure of phosphorylated RET tyrosine kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR	polymer	314	35788.2	1	UniProt (P07949) Pfam (PF07714)	HOMO SAPIENS (HUMAN)	RET RECEPTOR, C-RET
2	B, C (A)	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT) PubChem (284)
3	D (A)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505)
4	E (A)	water	water		18.0	62	Chemie (HOH)

Sequence modifications

A: 700 - 704 (PDB: 2IVT)
A: 705 - 1013 (UniProt: P07949)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35788.2
Non-Polymers*	Number of molecules	3
	Total formula weight	439.3
All*	Total formula weight	36227.5

*Water molecules are not included.